Happy Valentine’s Day to all our friends and patients!
Dr. Paul Amble, Dr. Nancy Cashman and the rest of the staff at Grand Avenue Dental want to thank our patients for making this award possible. We never could have won it without you giving us the chance to provide for your dental health and without you going back and providing feedback regarding your experience with us on Angie’s List.
Thank you for giving us the continued opportunity to provide you with excellent dental health care and service!
Paul, Nancy, Robin, Jamie, Linda, Janice, Vicki, Michelle, Tracy, Bob
Reader Submission from Stephen Tamiesie:
Cabin on Black Butte, Oregon - 2011
See more of his work here.
One might jump to the assumption that the only person crazy enough to collect over 1,800 tubes of toothpaste would be a dentist — and guess what? You’re right. At the moment, the only guy to have such a collection is, in fact, a dentist named Dr. Val Kolpakov from Saginaw, Michigan, who began his collection back in 2002, and it’s grown to include unusual flavors, misprinted tubes and historical samples. About one fourth of the items are on display in his office waiting room (He specializes in dentures, by the way). Some of the more unusual toothpastes include Hazelnut Chocolate from Italy (Um…okay), Scotch Whiskey 6 Proof and the 31 flavors of Breath Palette (Indian Curry, Pumpkin Pudding or Sweet Salt? How about neither?). The most valuable item in Dr. Val’s collection, is an antique Georgian tooth powder box, from 1801, that cost him $1,500. Back then toothpaste wasn’t even invented. Also, there is WWII era radioactive Doramund toothpaste, when people believed radioactive materials would help rebuild gum tissue. Again…WTF?
We’re happy to find out this dedicated obsessiveness has paid off. The Guinness World Records will soon recognize Dr. Val for having the world’s largest toothpaste collection.
And if you liked that Scotch Whiskey Toothpaste, there are plenty more alcoholic treats for you to brush with, just chose between bourbon, red wine, amaretto or champagne.
Emerging indications: antioxidants for periodontal disease
By Edward P. Allen, DDS, PhD
Since approximately 10 to 15 percent of adults worldwide suffer from periodontitis at one time or another(1), oral health professionals are constantly challenged with treating patients for existing conditions and helping them prevent future occurrences. Root planing, scaling, and in severe cases, surgical intervention are part of the standard treatment for periodontitis, and antibiotics are used for infection control.
However, in recent years, dental health professionals have honed in on the inflammation that accompanies periodontitis. Research shows that inflammation in the oral tissues—especially that associated with periodontitis—can be a factor in chronic illness such as heart and vascular disease, diabetes, arthritis, Alzheimer’s, pregnancy complications, and a growing list of other conditions.
The real culprit with inflammation is oxidative stress, a disturbance in the balance of oxidants and antioxidants. Oxidative stress is the result of overproduction of free radicals, unstable molecules that attack tissue cells by “stealing” electrons from other molecules.

Although infection is a major trigger for inflammation and oxidative stress, there are numerous other causes, such as poor diet, alcohol consumption and nicotine use or chemical pollutants. In oral tissues oxidative stress can result from dental procedures and from materials used for bleaching, composite fillings, implants, crowns, veneers, and so on.
Antibiotics control the micro-organisms that contribute to periodontitis and other infection, but they do not necessarily address the free radicals and oxidative stress that accompany inflammation.
Innate defense through natural salivary antibiotics and antioxidants
The human body has an innate defense system that combats oral inflammation: saliva. Saliva contains natural antibacterial compounds that defend against bacteria and other micro-organisms. Saliva also contains natural antioxidants that have been shown to neutralize free radicals contributing to oxidative stress and inflammation.
Several recent scientific articles have explored salivary antioxidants and their role in oral health, including periodontal disease, OLP, and even cancer.(2,3,4,5) There is a growing consensus that administration of local therapeutic agents (i.e., antioxidants) to the oral cavity should be considered.(6)
Topical antioxidants for inflammation control
Many dental health professionals have begun to augment the natural salivary antioxidants with topical application of antioxidants. A suite of products, AO ProVantage, from Dallas-based PerioSciences, LLC (www.periosciences.com), contain antioxidants, including phloretin and ferulic acid, that are applied directly to the gums. The products are distributed through professional dental offices and are best used as part of a comprehensive oral hygiene program.
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In the early 1990s, compounds of phloretin and ferulic acid were clinically proven to counteract free radicals that caused damage in skin cells. More recently, scientists at Texas A&M University Baylor College of Dentistry have shown that specific concentrations and combinations of phloretin and ferulic acid are highly effective at neutralizing free radicals in oral cells that are caused by nicotine, alcohol, and hydrogen peroxide—some of the most common toxins introduced to the oral cavity. Additional studies indicate that combinations of phloretin and ferulic acid may actually promote cell proliferation and healing in oral cells.(7)
Treating periodontal disease will continue to depend on antibiotics for micro-organisms. And now, augmenting natural salivary antioxidants with topical antioxidants on oral tissues shows promise in reducing free radicals, oxidative stress and oral inflammation. In the fight against periodontitis and other oral inflammation, topical antioxidants are taking their place next to antibiotics.






